I do. I bring a Fractal Fm3, Headrush 108, 2 guitars, and a bag of cables. I also own the lights so I bring them too. 2 trips to the truck. We play 3-4 hours, about 35-45 songs.
Like Rayneman above, I spent many years hauling 4x12's ,tube heads and pedal boards to my original band's gigs...