I like my 35 a lot (and I owned a 101B for ten years). My only playing 'out' these days is garage jams and my cab has a lot of low end, but the 35 has plenty volume and lows for me.
The 35 Blue is more like the 20th XTC, it will not do that smooth Vai tone the 101B Blue does, but I get a very good crunch from it, with that Bogner low-mids growl. Like the tone at the start of the second solo in Working Man when he's shredding on the low strings. Through Creamback 65s. The 35 Red IMO sounds like 101B Red crossed with 20th Red. I get saturated 80s metal tone on that channel easy.
The 35 has way too much gain IMO. I run Blue and Red gain at 9-10 o'clock. I played a 50 for a while; its gain structure was much more usable, but the gain tone had a smoothness or roundness in the lows that I didn't like, not the growl and bite in the 35 lows. I prefer the 35 tone, even though the 50 features were better.
IIRC the 35 FX loop issues were on the first ones made. The early ones also had a little knob by one of the transformers for external adjustment of the bias. So if you're shopping, maybe one without the bias knob also won't have the loop issues.