I had a run at building, and modding a few cabs. This is what I learned:
1. The more dry/cured the materials are, the better the cab sounds. This includes the wood, any adhesive, and finish. This allows the cab to resonate with with the sound, rather than dampen.
2. Stiff baffle = punchy
3. The center brace can be used to fine tune the cab, add/remove shims to it.
4. The back can be used to fine tune, try different materials, ply, mdf, etc..
Never been a fan of any of that poly fill, I removed it from my bogner 4x12, and it sounds way better.