suppose this is up for debate, but i'll say yes there could be some deference?
i'm basing my guess on my experience with the deference between 8ohm and 16ohm models of the same speaker, and from talking to a guy from Eminence about the deferences in the ohms. deferent ohms means slightly deferent voice coils.
for the most part, i perceive 16ohms to be a little brighter and a little less bass. if you look at frequency charts for Eminence speakers, there will be a little deference between the 16 and 8ohm models of the same speaker.
other people, including guys who's opinions i highly value, say they don't hear a deference between the 16 and 8 of the same speaker. so what do i know? just my 2 cents.