Regular 2x12s are definitely a nice bit smaller and lighter than 4x12s, so if you are on the go a lot and want to make things easier for yourself AND the sound of a regular 2x12 is good for YOU, they are a good option. But a lot of the upscale 2x12s these days are oversized anyway so the difference is a bit smaller though two speakers less can still make up to 10kg difference.
Practical disadvantage of regular 2x12s can be that the speakers most likely won't be pointing to your ears the way they do in a slanted 4x12. Some oversized cabs got a slightly slanted baffle, they make up for that. Or you work it out in placement.
That being said, a 4x12 is still a sound authority you can't quite touch even with the fattest oversized 2x12 and even mic'ed they sound different despite same speakers and all that. In terms of ease of mind of not blowing a speaker, it's also pretty clear which way to go.
The mesa recto cabs sound very uppermid-heavy for me and they provide for booooomy lows while your vh4 already has fucktons of lows, absolutely no need to fatten it up down there. You can't go wrong with a Diezel cab, they can keep up with the amp's power and keep the lows tight. Bogners are also good, so are Cornfords. Really, depends on what music you are playing and the sound you are going for. No two v30 (or whatever) cabs sound the same, wood and construction matter A LOT and the choice of the cab is almost as important if not equally important to the choice of amp.
Very typically, FL is for lots of attack and control and more modern styles while RL is a bit more forgiving and a bit less aggressive. But of course ultimately, this is up to YOUR own taste and you should DEFINITELY try the cab before buying it. You are in Frankfurt anyway, session/musikschmidt is right around the corner and they got a vh4, they got diezel cabs, bogner, cornford and mesa. By now they are also offering 3years warranty like thomann.
I have a practically mint Marshall v30 4x12 if you want it
