I wouldn't go that far. If you fry the tubes, other parts of the amp can also fry, including the PT, OT and resistors, and even other tubes. The 40 has fuse protection in case of output tube failure, but considering the problems with transformers in Egnater amps, I would err on the side of caution myself. Although my feeling is that these tubes would work well in the 40 or similar amp, you're still taking a chance. You might want to contact Egnater and see what they say about it, CYA as far as warranty.