The only downside is that it really changes the entire voice of the amp. So if you are shooting for a specific sound and you’re already close, it’ll throw you off quite a bit.
I personally enjoy the response of the big low end temporarily, but it is a little too much to be permanent for me. There’s a limit where it’s just a bit overboard.
If you think about how it works, the .0022 is blocking any frequency lower than its value from getting into the NFB circuit. So all the midrange and lows that would not be able to pass the .0022 are now not being able to be cancelled out and therefore make it to the speaker. This actually makes NFB sort of easier to understand.
With the above being said, you can then tune which frequencies are making it through into the NFB by adjusting the value of the cap in series. That .1uF will pass a lot more low mid and lows. So then they are cancelled and you hear less of them. Of course you can use any value you want and see what sounds right, if any.