Besides my computer rig, I've been on an amp purchasing effort, most recently a custom build from Ceriatone of an AC-100 MkII.
Late last year I picked up a "floor preamp" - ISP Theta DSP Pro - Michael Sweet and it sounded amazing, '80s in a box. I picked up an ISP Steal Pro solid state amp to run the stage out into it then into a Mesa Compact 2x12; I also ran the direct outs into a powered PA with the limited cab sims (not IR based), and it sounded very good too.
Next up, I plan to run the Theta Pro stage outs (L & R) into my Engl E850/100 Power amp, with each side going into an Engl PRO E212VHB. I have to move a few things around, those cabs are currently connected to my Engl E651 Artist Edition head.
FWIW, the ISP Theta Pro is an old school rack preamp / effects in a floor controller; it's not a modeler. If you have power amp and guitar cabs you like, you can find a Marshall/Mesa etc. preamp setting thanks to all the EQ controls. It's tedious to program, just like an ADA MP-1 or MP-2.
I got mine used, in like new condition, at a great price.