Three way tie: PRS Custom 24, ESP Horizon FR27 with frets 13-27 scalloped, and Jackson USA RR1. I have a few others that come close but those are the best.
On the other hand, I like guitars to fight back a little bit, too. Like my Gibson Firebird V. It's top heavy (old-school banjo tuners), so I have to keep a good hold on it, or either of my Gibson LPCs. By the nut, they're easy, but get close to the heel, well, everyone knows they're pretty thick. Gotta reach for those last few notes, gotta really WANT them... and that's why I like it that way.