Im leaning towards the Es-8.
What i like about the OC10 is the 10 loops and the easy to create/edit a preset.
Also, in the "Manual" mode i can still chance my amp channel, as if was one pedal. Im not sure if the ES-8 has this possibility.
Now, the ES-8 has lots of features that the OC10 doesn't. Like changing the pedals order, possibility of delay leaving trail...
One other thing that i like about the ES-8 is that I can, in any preset, set one or more bbuttons to act as a pedal, like the "stompbox" of the gigrig G2.
My gear is not complicated, and im afraid i will under use the ES-8:
Guitar > Digitech Drop > Fulltone Wah > SP compressor > Tube Screamer > DS-2 > BigMuff > Phase90 > MXR chorus > MicroAmp > Line6 DL4
I will add the Line6 M5 soon. Thats why im thinking about the ES-8. Since the M5 has distortions, delays, modulation, ect, i will need to br able to change its position in the chain!