For me these days, it’s a medium output Humbucker in the bridge with a Little 59 in the neck. I love the clean tones I get with singles in the neck, but I often find the output lagging behind the bridge Humbucker on overdriven tones. I recently tried a Little ‘59 in the neck and love it. Definitely has its own thing going on. Has the clean chimey-ness of a true single coil with more oomph.