We had some of this discussion a while back about slant vs. straight and dialing in an amp. I think it turned into a big shit-fest. More often than not, with straight cabs a guy will be dialed in much brighter than need be. If you are playing on a 3 or 4 foot shallow stage, the peeps in front are getting pelted with the excess top end because you can't really tell it while standing. You almost have to get on your knees to hear what is happening. A slant will help you out in this regard and in general for hearing yourself as long as you are near the cab. As someone mentioned, mic'd and the FOH, there won't be any difference. If you have road cases for your heads, sitting your cabs up on these will remedy that, or some sort of riser. Someone mentioned Adam Jones, and you will always see his straight cab on risers. You can try those "dispersion bra's" or whatever they call them too.
Steve