While it's not a bolt-on, I have an Ibanez RGT320 neck-through mahogany body w/maple top, 5-pc maple/walnut neck, looks like a dark and dense rosewood fretboard, locking trem. It has a DiMarzio AT-1 in the bridge, Liquifire in the neck. It has a thick midrange but not in a bad way, surprisingly brighter high end but not tinny, and the AT-1 adds some upper mids and tightens up the bass. Overall I find the sound is thick and more aggressive through a reasonably wide spectrum, warm yet edgy for distorted harder rock/metal and lead work; cleans are full with a bit of sparkle. I'm used to a Duncan JB so my ear is tuned to more upper mids with this combo, yet I never find any freq. range overpowering. This guitar is no light weight but it's not quite as heavy as other mahogany bodied guitars I've tried in the past like some LPs.
Comparing my Ibanez J Custom bolt-on with alder body/maple top, maple/walnut neck (this neck is predominantly maple), rosewood fretboard, locking trem, this guitar sounds more balanced and even throughout the low mids to highs, a bit scooped because of the stock Custom 5 bridge pickup, and has this snarl to it. It's not as agressive in the mids as the mahogany RGT, but it is hard to compare with the different pickups in both guitars. This guitar and stock pickup combo is great for smoother 80s metal tones, though its rhythm tones tend to not stand out as much in a mix (and I play through V30s).
My most verstaile sounding guitar is the neck-through ESP LTD Elite Horizon-III with alder wings, maple top, 3-pc. maple neck, ebony fretboard, Floyd Rose. It has a Jazz neck and JB bridge pups. It came stock with the Custom 5 but for some reason all I was getting was a thick mid range with no highs, so I swapped it out for an old 90s JB and got my upper mids and high end back. Not quite as thick sounding as my mahogany RGT but not as "thin" as the alder JC. Not lacking for leads or rhythms. This guitar is fairly light weight due to its smaller body.
I have an older Brian Moore mahogany bolt-on that's really light weight and supposedly comes with a JB bridge though I've never confirmed it. It's a fixed bridge with thicker strings I occasionally use for alternate tunings. This thing sounds totally bad ass when tuned lower, very thick and juicy (lower) mids.
Maybe it's the pickups in mahogany super strats that's a big factor. I tend towards JB flavored pups it seems, AT-1, and even my Peavey HP has custom pups supposedly wound to JB-like specs (A5 mag @ 16.4 kohm). They have that upper mid push, they don't work for some people but seems to work for me though.
I also tend to have guitars with maple tops, there seems to be more sizzle in the sound that I like.
Having said all that, I'm tuned to E-standard and my rig is more on the modern side: Rhodes Colossus through V30s, i.e. it's not in the Marshall vein of amps, so YMMV greatly.