His method of gain on 10, then boost is just like a friend of mine. He used to (died last year) go gain 10, BASS 10, treble 6-7, mids 3-4, presence 4-6 on every amp. EVERY AMP. And then boost it with a Tube Screamer, also with the gain on 10.
Made pretty much everything sound like shit. I say that with love. Really nice guy, and as good a "shredder" as I've ever known, but dude was a bit too high on himself from a gear perspective because he had played pretty much everything of note up until say 2010. But he didn't really make any of them exhibit good tone.